Research publications
2005

1. Atzei A, Gajewska K, Huggon IC, Allan L, Nicolaides KH.
   Relation between nuchal translucency thickness and prevalence of major cardiac defects in fetuses with normal karyotype.
   Ultrasound Obstet Gynecol 2005;26:154-7 pdf
2. Avgidou K, Papageorghiou A, Bindra R, Spencer K, Nicolaides KH.
   Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.
   Am J Obstet Gynecol 2005;192:1761-7
3. Banerjee S, Smallwood A, Moorhead J, Chambers AE, Papageorghiou A, Campbell S, Nicolaides K.
   Placental expression of IFN-gamma and its receptor IFN-gammaR2 fail to switch from early hypoxic to late normotensive development in pre-eclampsia.
   J Clin Endocrinol Metab 2005;90:944-52
4. Banerjee S, Smallwood A, Chambers AE, Papageorghiou A, Loosfelt H, Spencer K, Campbell S, Nicolaides K.
   A link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnancies.
   Reprod Biol Endocrinol 2005; 3:25
5. Chaoui R, Levaillant JM, Benoit B, Faro C, Wegrzyn P, Nicolaides KH.
   Three-dimensional sonographic description of abnormal metopic suture in second- and third-trimester fetuses.
   Ultrasound Obstet Gynecol 2005;26:761-4 pdf
6. Chatzimeletiou K, Makrydimas G, Sotiriadis A, Paraskevaidis E, Nicolaides KH.
   Aneuploidy screening in coelomic samples using fluorescence in situ hybridisation (FISH).
   Prenat Diagn 2005;25:919-26 pdf
7. Chiu RW, Lui WB, El-Sheikhah A, Chan AT, Lau TK, Nicolaides KH, Lo YM.
   Comparison of protocols for extracting circulating DNA and RNA from maternal plasma.
   Clin Chem 2005;51:2209-10
8. Cicero S, Spencer K, Avgidou K, Faiola S, Nicolaides KH.
   Maternal serum biochemistry at 11-13(+6) weeks in relation to the presence or absence of the fetal nasal bone on ultrasonography in chromosomally abnormal fetuses: an updated analysis of integrated ultrasound and biochemical screening.
   Prenat Diagn 2005;25:977-83 pdf
9. Cuckle HS, Spencer K, Nicolaides KH.
   Down syndrome screening marker levels in women with a previous aneuploidy pregnancy.
   Prenat Diagn 2005;25:47-50 pdf
10. Deprest J, Jani J, Gratacos E, Vandecruys H, Naulaers G, Delgado J, Greenough A, Nicolaides K; FETO Task Group.
    Fetal intervention for congenital diaphragmatic hernia: the European experience.
    Semin Perinatol 2005;29:94-103
11. Erasmus I, Nicolaou E, van Gelderen CJ, Nicolaides KH.
    Cervical length at 23 weeks gestation-relation to demographic characteristics and previous obstetric history in South African women.
    S Afr Med J 2005;95:691-5
12. Faiola S, Tsoi E, Huggon IC, Allan LD, Nicolaides KH.
    Likelihood ratio for trisomy 21 in fetuses with tricuspid regurgitation at the 11 to 13 + 6-week scan.
    Ultrasound Obstet Gynecol 2005;26:22-7 pdf
13. Falcon O, Peralta CF, Cavoretto P, Faiola S, Nicolaides KH.
    Fetal trunk and head volume measured by three-dimensional ultrasound at 11 + 0 to 13 + 6 weeks of gestation in chromosomally normal pregnancies.
    Ultrasound Obstet Gynecol 2005;26:263-266 pdf
14. Falcon O, Wegrzyn P, Faro C, Peralta CF, Nicolaides KH.
    Gestational sac volume measured by three-dimensional ultrasound at 11 to 13 + 6 weeks of gestation: relation to chromosomal defects.
    Ultrasound Obstet Gynecol 2005;25:546-50 pdf
15. Falcon O, Cavoretto P, Peralta CF, Csapo B, Nicolaides KH.
    Fetal head-to-trunk volume ratio in chromosomally abnormal fetuses at 11 + 0 to 13 + 6 weeks of gestation.
    Ultrasound Obstet Gynecol 2005;26:755-60 pdf
16. Faro C, Wegrzyn P, Benoit B, Chaoui R, Nicolaides KH.
    Metopic suture in fetuses with holoprosencephaly at 11 + 0 to 13 + 6 weeks of gestation.
    Utrasound Obstet Gynecol 2005;27:162-166 pdf
17. Faro C, Benoit B, Wegrzyn P, Chaoui R, Nicolaides KH.
    Three-dimensional sonographic description of the fetal frontal bones and metopic suture.
    Ultrasound Obstet Gynecol 2005;26:618-21 pdf
18. Jani J, Gratacos E, Greenough A, Piero JL, Benachi A, Harrison M, Nicolaides K, Deprest J; the FETO TASK GROUP.
    Percutaneous fetal endoscopic tracheal occlusion (FETO) for severe left-sided congenital diaphragmatic hernia.
    Cin Obstet Gynecol 2005;48:910-922
19. Makrydimas G, Vandecruys H, Sotiriadis A, Lakasing L, Spencer K, Nicolaides KH.
    Coelomic fluid leptin concentration in normal first-trimester pregnancies and missed miscarriages.
    Fetal Diagn Ther 2005;20:406-9 pdf
20. Nicolaides KH.
    First-Trimester Screening for Chromosomal Abnormalities.
    Semin Perinatol 2005;29:190-194
21. Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O.
    Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening.
    Ultrasound Obstet Gynecol 2005;25:221-6 pdf
22. Nicolaides KH, Chervenak FA, McCullough LB, Avgidou K, Papageorghiou A.
    Evidence-based obstetric ethics and informed decision-making by pregnant women about invasive diagnosis after first-trimester assessment of risk for trisomy 21.
    Am J Obstet Gynecol 2005;193:322-6
23. Papageorghiou AT, Yu CK, Erasmus IE, Cuckle HS, Nicolaides KH.
    Assessment of risk for the development of pre-eclampsia by maternal characteristics and uterine artery Doppler.
    BJOG 2005;112:703-9
24. Peralta CF, Falcon O, Wegrzyn P, Faro C, Nicolaides KH.
    Assessment of the gap between the fetal nasal bones at 11 to 13 + 6 weeks of gestation by three-dimensional ultrasound.
    Ultrasound Obstet Gynecol 2005;25:464-7 pdf
25. Peralta CF, Cavoretto P, Csapo B, Vandecruys H, Nicolaides KH.
    Assessment of lung area in normal fetuses at 12-32 weeks.
    Ultrasound Obstet Gynecol 2005;26:718-24 pdf
26. Peralta CF, Cavoretto P, Csapo B, Falcon O, Nicolaides KH.
    Lung and heart volumes by three-dimensional ultrasound in normal fetuses at 12-32 weeks' gestation.
    Ultrasound Obstet Gynecol 2005;27:128-133 pdf
27. Rane SM, Guirgis RR, Higgins B, Nicolaides KH.
    Models for the prediction of successful induction of labor based on pre-induction sonographic measurement of cervical length.
    J Matern Fetal Neonatal Med 2005;17:315-22
28. Rijhwani A, Davenport M, Dawrant M, Dimitriou G, Patel S, Greenough A, Nicolaides K.
    Definitive surgical management of antenatally diagnosed exomphalos.
    J Pediatr Surg 2005;40:516-22
29. Sepulveda W, Surerus E, Vandecruys H, Nicolaides KH.
    Fetofetal transfusion syndrome in triplet pregnancies: Outcome after endoscopic laser surgery.
    Am J Obstet Gynecol 2005;192:161-4
30. Souka AP, Von Kaisenberg CS, Hyett JA, Sonek JD, Nicolaides KH.
    Increased nuchal translucency with normal karyotype.
    Am J Obstet Gynecol 2005;192:1005-21
31. Spencer K, Yu CK, Cowans NJ, Otigbah C, Nicolaides KH.
    Prediction of pregnancy complications by first-trimester maternal serum PAPP-A and free beta-hCG and with second-trimester uterine artery Doppler.
    Prenat Diagn 2005;25:949-53 pdf
32. Spencer K, Heath V, El-Sheikhah A, Ong CY, Nicolaides KH.
    Ethnicity and the need for correction of biochemical and ultrasound markers of chromosomal anomalies in the first trimester: a study of Oriental, Asian and Afro-Caribbean populations.
    Prenat Diagn 2005;25:365-9 pdf
33. Spencer K, Cicero S, Atzei A, Otigbah C, Nicolaides KH.
    The influence of maternal insulin-dependent diabetes on fetal nuchal translucency thickness and first-trimester maternal serum biochemical markers of aneuploidy.
    Prenat Diagn 2005;25:927-9 pdf
34. Spencer K, Crossley JA, Aitken DA, Nicolaides KH.
    Second-trimester levels of pregnancy-associated plasma protein-A and free beta-hCG in pregnancies with trisomy 13.
    Prenat Diagn 2005;25:358-61 pdf
35. Spencer K, Yu CK, Rembouskos G, Bindra R, Nicolaides KH.
    First trimester sex hormone-binding globulin and subsequent development of preeclampsia or other adverse pregnancy outcomes.
    Hypertens Pregnancy 2005;24:303-11
36. Tsoi E, Fuchs IB, Rane S, Geerts L, Nicolaides KH.
    Sonographic measurement of cervical length in threatened preterm labor in singleton pregnancies with intact membranes.
    Ultrasound Obstet Gynecol 2005;25:353-6 pdf
37. Tsui NB, Chiu RW, Ding C, El-Sheikhah A, Leung TN, Lau TK, Nicolaides KH, Lo YM.
    Detection of trisomy 21 by quantitative mass spectrometric analysis of single-nucleotide polymorphisms.
    Clin Chem 2005;51:2358-62
38. Yu CK, Smith GC, Papageorghiou AT, Cacho AM, Nicolaides KH.
    An integrated model for the prediction of preeclampsia using maternal factors and uterine artery Doppler velocimetry in unselected low-risk women.
    Am J Obstet Gynecol 2005;193:429-36
39. Vandecruys H, Faiola S, Auer M, Sebire N, Nicolaides KH.
    Screening for trisomy 21 in monochorionic twins by measurement of fetal nuchal translucency thickness.
    Ultrasound Obstet Gynecol 2005;25:551-3 pdf
40. Wegrzyn P, Faro C, Falcon O, Peralta CF, Nicolaides KH.
    Placental volume measured by three-dimensional ultrasound at 11 to 13 + 6 weeks of gestation: relation to chromosomal defects.
    Ultrasound Obstet Gynecol 2005;26:28-32 pdf
41. Zimmermann B, El-Sheikhah A, Nicolaides K, Holzgreve W, Hahn S.
    Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma.
    Clin Chem 2005;51:1598-1604

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