Research
Research publications

2011

  1. Akolekar R, Bower S, Flack N, Bilardo CM, Nicolaides KH.
    Prediction of miscarriage and stillbirth at 11-13 weeks and the contribution of chorionic villus sampling.
    Prenat Diagn 2011;31:38-45 pdf
  2. Akolekar R, Syngelaki A, Sarquis R, Zvanca M, Nicolaides KH.
    Prediction of early, intermediate and late pre-eclampsia from maternal factors, biophysical and biochemical markers at 11-13 weeks.
    Prenat Diagn 2011;31:66-74 pdf erratum
  3. Akolekar R, Cruz JJ, Penco JM, Zhou Y, Nicolaides KH.
    Maternal plasma plasminogen activator inhibitor-2 at 11 to 13 Weeks of gestation in hypertensive disorders of pregnancy.
    Hypertens Pregnancy 2011;30:194-202
  4. Akolekar R, Finning K, Kuppusamy R, Daniels G, Nicolaides KH.
    Fetal RHD Genotyping in Maternal Plasma at 11-13 Weeks of Gestation.
    Fetal Diagn Ther 2011;29:301-6 pdf
  5. Ashoor G, Maiz N, Cuckle H, Jawdat F, Nicolaides KH.
    Maternal thyroid function at 11-13 weeks of gestation in fetal trisomies 21 and 18.
    Prenat Diagn 2011;31:33-7 pdf
  6. Ashoor G, Maiz N, Rotas M, Jawdat F, Nicolaides KH.
    Maternal thyroid function at 11-13 weeks of gestation and spontaneous preterm delivery.
    Obstet Gynecol 2011;117:293-8
  7. Beta J, Akolekar R, Ventura W, Syngelaki A, Nicolaides KH.
    Prediction of spontaneous preterm delivery from maternal factors, obstetric history and placental perfusion and function at 11-13 weeks.
    Prenat Diagn 2011;31:75-83 pdf
  8. Beta J, Szekeres-Bartho J, Skyfta E, Akolekar R, Nicolaides KH.
    Maternal serum progesterone-induced blocking factor at 11-13 weeks gestation in spontaneous early preterm delivery.
    Fetal Diagn Ther 2011;29:197-200 pdf
  9. Beta J, Bredaki FE, Calvo JR, Akolekar R, Nicolaides KH.
    Maternal serum a-fetoprotein at 11-13 weeks' gestation in spontaneous early preterm delivery.
    Fetal Diagn Ther 2011;30:88-93 pdf
  10. Bombard AT, Akolekar R, Farkas DH, Vanagtmael AL, Aquino F, Oeth P, Nicolaides KH.
    Fetal RHD genotype detection from circulating cell-free fetal DNA in maternal plasma in non-sensitized RhD negative women.
    Prenat Diagn 201;31:802-8 pdf
  11. Bredaki FE, Wright D, Matos P, Syngelaki A, Nicolaides KH.
    First-Trimester Screening for Trisomy 21 Using Alpha-Fetoprotein.
    Fetal Diagn Ther 2011;30:215-8 pdf
  12. NewBredaki FE, Wright D, Akolekar R, Cruz G, Nicolaides KH.
    Maternal serum alpha-fetoprotein in normal pregnancy at 11-13 weeks' gestation.
    Fetal Diagn Ther 2011;30:274-9 pdf
  13. Carbone IF, Cruz JJ, Sarquis R, Akolekar R, Nicolaides KH.
    Assisted conception and placental perfusion assessed by uterine artery Doppler at 11-13 weeks' gestation.
    Hum Reprod 2011;26:1659-64
  14. Cetin I, Huppertz B, Burton G, Cuckle H, Gonen R, Lapaire O, Mandia L, Nicolaides K, Redman C, Soothill P, Spencer K, Thilaganathan B, Williams D, Meiri H.
    Pregenesys pre-eclampsia markers consensus meeting: What do we require from markers, risk assessment and model systems to tailor preventive strategies?
    Placenta 2011;32:S4-16
  15. Chaveeva P, Carbone IF, Syngelaki A, Akolekar R, Nicolaides KH.
    Contribution of Method of Conception on Pregnancy Outcome after the 11-13 Weeks Scan.
    Fetal Diagn Ther 2011;30:9-22 pdf
  16. Chelemen T, Syngelaki A, Maiz N, Allan L, Nicolaides KH.
    Contribution of ductus venosus doppler in first-trimester screening for major cardiac defects.
    Fetal Diagn Ther 2011;29:127-34 pdf
  17. Chen M, Wang HF, Leung TY, Sahota DS, Borenstein M, Nicolaides K, Lao TT, Lau TK.
    Frontomaxillary facial angle at 11 + 0 to 13 + 6 weeks in Chinese population.
    J Matern Fetal Neonatal Med 2011;24:498-501
  18. Chen EZ, Chiu RW, Sun H, Akolekar R, Chan KC, Leung TY, Jiang P, Zheng YW, Lun FM, Chan LY, Jin Y, Go AT, Lau ET, To WW, Leung WC, Tang RY, Au-Yeung SK, Lam H, Kung YY, Zhang X, van Vugt JM, Minekawa R, Tang MH, Wang J, Oudejans CB, Lau TK, Nicolaides KH, Lo YM.
    Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing.
    PLoS One 2011;6:21791 pdf
  19. Chiu RW, Akolekar R, Zheng YW, Leung TY, Sun H, Chan KC, Lun FM, Go AT, Lau ET, To WW, Leung WC, Tang RY, Au-Yeung SK, Lam H, Kung YY, Zhang X, van Vugt JM, Minekawa R, Tang MH, Wang J, Oudejans CB, Lau TK, Nicolaides KH, Lo YM.
    Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study.
    BMJ 2011;342:c7401 pdf
  20. Deprest J, Nicolaides K, Done' E, Lewi P, Barki G, Largen E, Dekoninck P, Sandaite I, Ville Y, Benachi A, Jani J, Amat-Roldan I, Gratacos E.
    Technical aspects of fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia.
    J Pediatr Surg 2011;46:22-32
  21. Deprest JA, Nicolaides K, Gratacos E.
    Fetal surgery for congenital diaphragmatic hernia is back from never gone.
    Fetal Diagn Ther 2011;29:6-17 pdf
  22. Derwig IE, Akolekar R, Zelaya FO, Gowland PA, Barker GJ, Nicolaides KH.
    Association of placental volume measured by MRI and birth weight percentile.
    J Magn Reson Imaging 2011;34:1125-30
  23. Ferreira AF, Rezende JC, Vaikousi E, Akolekar R, Nicolaides KH.
    Maternal serum visfatin at 11-13 Weeks of gestation in gestational diabetes mellitus.
    Clin Chem 2011;57:609-13
  24. Giambona A, Makrydimas G, Leto F, Damiani G, Jakil MC, Picciotto F, Renda D, Fiorino R, Renda MC, Schillaci G, Gueli-Alletti D, Nicolaides KH, Maggio A.
    Feasibility of DNA diagnosis of haemoglobinopathies on coelocentesis.
    Br J Haematol 2011;153,268-272
  25. Gielchinsky Y, Zvanca M, Minekawa R, Persico N, Nicolaides KH.
    Liver volume in trisomy 21 and euploid fetuses at 11 to 13 weeks.
    Prenat Diagn 2011;31:28-32 pdf
  26. Gielchinsky Y, Zvanca M, Akolekar R, Calvo JR, Nicolaides KH.
    Adrenal gland length in euploid and trisomy 18 fetuses at 11-13 weeks.
    Prenat Diagn 2011;31:773-7 pdf
  27. Greco E, Lange A, Ushakov F, Calvo JR, Nicolaides KH.
    Prediction of spontaneous preterm delivery from endocervical length at 11 to 13 weeks.
    Prenat Diagn 2011;31:84-9 pdf
  28. Jani J, Valencia C, Cannie M, Vuckovic A, Sellars M, Nicolaides KH.
    Tracheal diameter at birth in severe congenital diaphragmatic hernia treated by fetal endoscopic tracheal occlusion.
    Prenat Diagn 2011;31:699-704 pdf
  29. Karagiannis G, Akolekar R, Sarquis R, Wright D, Nicolaides KH."
    Prediction of small-for-gestation neonates from biophysical and biochemical markers at 11-13 weeks.
    Fetal Diagn Ther 2011;29:148-54 pdf
  30. Karagiannis G, Ashoor G, Maiz N, Jawdat F, Nicolaides KH.
    Maternal thyroid function at eleven to thirteen weeks of gestation and subsequent delivery of small for gestational age neonates.
    Thyroid 2011;21:1127-31
  31. Klein K, Rode L, Nicolaides K, Krampl-Bettelheim E, Tabor A; PREDICT Group.
    Vaginal micronized progesterone and the risk of preterm delivery in high-risk twin pregnancies - secondary analysis of a placebo-controlled randomized trial and meta-analysis
    Ultrasound Obstet Gynecol 2011;38:281-7 pdf
  32. Lachmann R, Chaoui R, Moratalla J, Picciarelli G, Nicolaides KH.
    Posterior brain in fetuses with open spina bifida at 11 to 13 weeks.
    Prenat Diagn 2011;31:103-6 pdf
  33. Lopez MF, Kuppusamy R, Sarracino DA, Prakash A, Athanas M, Krastins B, Rezai T, Sutton JN, Peterman S, Nicolaides K.
    Mass spectrometric discovery and selective reaction monitoring (SRM) of putative protein biomarker candidates in first trimester trisomy 21 maternal serum.
    J Proteome Res 2011 7;10:133-42 pdf
  34. Madsen HN, Ball S, Wright D, Tørring N, Petersen OB, Nicolaides KH, Spencer K.
    A reassessment of biochemical marker distributions in trisomy 21-affected and unaffected twin pregnancies in the first trimester.
    Ultrasound Obstet Gynecol 2011;37:38-47 pdf
  35. Mastricci AL, Akolekar R, Kuppusamy R, Ahmed M, Nicolaides KH.
    Are Serum Protein Biomarkers Derived from Proteomic Analysis Useful in Screening for Trisomy 21 at 11-13 Weeks?
    Fetal Diagn Ther 2011;30:53-9 pdf
  36. Matias A, Maiz N, Montenegro N, Nicolaides K.
    Ductus venosus flow at 11-13 weeks in the prediction of birth weight discordance in monochorionic twins.
    J Perinat Med 2011;39(4):467-70
  37. Makgoba M, Nelson SM, Savvidou M, Messow CM, Nicolaides K, Sattar N.
    First-trimester circulating 25-hydroxyvitamin d levels and development of gestational diabetes mellitus.
    Diabetes Care 2011;34:1091-3
  38. Nanda S, Savvidou M, Syngelaki A, Akolekar R, Nicolaides KH.
    Prediction of gestational diabetes mellitus by maternal factors and biomarkers at 11 to 13 weeks.
    Prenat Diagn 2011;31:135-41 pdf
  39. Nanda S, Akolekar R, Sarquis R, Mosconi AP, Nicolaides KH
    Maternal serum adiponectin at 11-13 weeks of gestation in predicition of macrosomia.
    Prenat Diag 2011;31:479-83 pdf
  40. Nanda S, Yu CK, Giurcaneanu L, Akolekar R, Nicolaides KH.
    Maternal serum adiponectin at 11-13 weeks of gestation in preeclampsia.
    Fetal Diagn Ther 2011;29:208-15 pdf
  41. Nanda S, Akolekar R, Sodre D, Vaikousi E, Nicolaides KH.
    Maternal serum adiponectin at 11-13 weeks of gestation in pregnancies delivering small for gestation neonates.
    Fetal Diagn Ther 2011;29:274-9 pdf
  42. Nicolaides KH.
    A model for a new pyramid of prenatal care based on the 11 to 13 weeks' assessment.
    Prenat Diagn 2011;31:3-6 pdf
  43. Nicolaides KH.
    Turning the pyramid of prenatal care.
    Fetal Diagn Ther 2011;29:183-96 pdf
  44. Nicolaides KH.
    Screening for fetal aneuploidies at 11 to 13 weeks.
    Prenat Diagn 2011;31:7-15 pdf
  45. Nicolaides KH, Chitty LS.
    Fetal therapy: progress made and lessons learnt.
    Prenat Diagn 2011;31:619-20 pdf
  46. Papaioannou GK, Syngelaki A, Maiz N, Ross JA, Nicolaides KH.
    Sonographic markers of aneuploidies at 6-10 weeks of gestation.
    Early Hum Dev 2011;87:453-6
  47. Papaioannou GI, Syngelaki A, Maiz N, Ross JA, Nicolaides KH.
    Ultrasonographic prediction of early miscarriage.
    Hum Reprod. 2011;26:1685-92
  48. Papaioannou GI, Syngelaki A, Maiz N, Ross JA, Nicolaides KH
    Prediction of outcome in dichorionic twin pregnancies at 6-10 weeks' gestation.
    Am J Obstet Gynecol 2011;205:3481-5
  49. Pereira S, Ganapathy R, Syngelaki A, Maiz N, Nicolaides KH.
    Contribution of fetal tricuspid regurgitation in first-trimester screening for major cardiac defects.
    Obstet Gynecol 2011;117:1384-91
  50. Persico N, Moratalla J, Lombardi C, Zidere V, Allan L, Nicolaides KH.
    Fetal echocardiography at 11-13 weeks by transabdominal high frequency ultrasound.
    Ultrasound Obstet Gynecol 2011;37:296-301 pdf
  51. Plasencia W, Akolekar R, Dagklis T, Veduta A, Nicolaides KH.
    Placental volume at 11-13 weeks' gestation in the prediction of birth weight percentile.
    Fetal Diagn Ther 2011;30:23-8 pdf
  52. Plasencia W, Garcia R, Pereira S, Akolekar R, Nicolaides KH.
    Criteria for screening and diagnosis of gestational diabetes mellitus in the first trimester of pregnancy.
    Fetal Diagn Ther 2011;30:108-15 pdf
  53. Poon LC, Kametas NA, Valencia C, Chelemen T, Nicolaides KH.
    Hypertensive disorders in pregnancy: screening by systolic diastolic and mean arterial pressure at 11-13 weeks.
    Hypertens Pregnancy 2011;30:93-107
  54. Poon LC, Karagiannis G, Staboulidou I, Shafiei A, Nicolaides KH.
    Reference range of birth weight with gestation and first-trimester prediction of small-for-gestation neonates.
    Prenat Diagn 2011;31:58-65 pdf
  55. Poon LC, Karagiannis G, Stratieva V, Syngelaki A, Nicolaides KH.
    First-trimester prediction of macrosomia.
    Fetal Diagn Ther 2011;29:139-47 pdf
  56. Prendergast M, Rafferty G, Davenport M, Persico N, Jani J, Nicolaides K, Greenough A.
    Three-dimensional ultrasound fetal lung volumes and infant respiratory outcome: a prospective observational study.
    BJOG 2011;118:608-14
  57. Rode L, Klein K, Nicolaides K, Krampl-Bettelheim E, Tabor A; PREDICT Group.
    Prevention of preterm delivery in twin gestations (PREDICT): A multicentre randomised placebo-controlled trial on the effect of vaginal micronised progesterone.
    Ultrasound Obstet Gynecol 2011;38:272-80 pdf
  58. Savvidou MD, Kaihura C, Anderson JM, Nicolaides KH.
    Maternal arterial stiffness in women who subsequently develop pre-eclampsia.
    PLoS One 2011;6:e18703 pdf
  59. Savvidou M, Samuel I, Syngelaki A, Poulton M, Nicolaides K.
    First-trimester markers of aneuploidy in women positive for HIV.
    BJOG 2011;118:844-8
  60. Savvidou M, Akolekar R, Samaha R, Masconi A, Nicolaides Kh.
    Maternal serum 25-hydroxyvitamin D levels at 11(+0) -13(+6) weeks in pregnant women with diabetes mellitus and in those with macrosomic neonates.
    BJOG 2011;118:951-5
  61. Savvidou M, Samuel M, Akolekar R, Poulton M, Nicolaides K.
    First trimester maternal uterine artery Doppler examination in HIV-positive women.
    HIV Med 2011;12:632-6
  62. Sifakis S, Akolekar R, Mantas N, Kappou D, Nicolaides KH.
    Maternal serum human placental growth hormone (hPGH) at 11 to 13 weeks of gestation in preeclampsia.
    Hypertens Pregnancy 2011;30:74-82
  63. Sifakis S, Akolekar R, Kappou D, Mantas N, Nicolaides KH.
    Maternal serum insulin-like growth factor-binding protein-1 (IGFBP-1) at 11-13 weeks in pre-eclampsia.
    Prenat Diagn 2011;31:196-201 pdf
  64. Sifakis S, Akolekar R, Kappou D, Mantas N, Nicolaides KH.
    Maternal serum IGF-I, IGFBP-1 and IGFBP-3 at 11-13 weeks in trisomy 21 and trisomy 18 pregnancies.
    Eur J Obstet Gynecol Reprod Biol 2011;157:166-8
  65. Staboulidou I, Pereira S, Cruz JJ, Syngelaki A, Nicolaides KH.
    Prevalence and Outcome of Absence of Ductus Venosus at 11 to 13(+6) Weeks.
    Fetal Diagn Ther 2011;30:35-40 pdf
  66. Syngelaki A, Chelemen T, Dagklis T, Allan L, Nicolaides KH.
    Challenges in the diagnosis of fetal non-chromosomal abnormalities at 11-13 weeks.
    Prenat Diagn 2011;31:90-102 pdf
  67. NewSyngelaki A, Bredaki FE, Vaikousi E, Maiz N, Nicolaides KH.
    Body Mass Index at 11-13 Weeks' Gestation and Pregnancy Complications.
    Fetal Diagn Ther 2011;30:250-65 pdf
  68. Turan OM, Turan S, Berg C, Gembruch U, Nicolaides KH, Harman CR, Baschat AA.
    The duration of persistent abnormal ductus venosus flow and its impact on perinatal outcome in fetal growth restriction.
    Ultrasound Obstet Gynecol 2011 Sep;38(3):295-302 pdf
  69. Wright D, Syngelaki A, Staboulidou I, Cruz JJ, Nicolaides KH.
    Screening for trisomies in dichorionic twins by measurement of fetal nuchal translucency thickness according to the mixture model.
    Prenat Diagn 2011;31:16-21 pdf
  70. Wright D, Syngelaki A, Birdir C, Bedei I, Nicolaides KH.
    First-Trimester Screening for Trisomy 21 with Adjustment for Biochemical Results of Previous Pregnancies.
    Fetal Diagn Ther 2011;30:194-202 pdf
  71. Yu CK, Ertl R, Samaha R, Akolekar R, Nicolaides KH.
    Normal range of maternal serum vitamin D at 11-13 weeks gestation.
    Fetal Diagn Ther 2011;30:94-9 pdf
  72. Zvanca M, Gielchinsky Y, Abdeljawad F, Bilardo CM, Nicolaides KH.
    Hepatic artery Doppler in trisomy 21 and euploid fetuses at 11-13 weeks.
    Prenat Diagn 2011;31:22-7 pdf

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